Clinical Study on the Melarsoprol-Related Encephalopathic Syndrome: Risk Factors and HLA Association

Clinical Study on the Melarsoprol-Related Encephalopathic Syndrome: Risk Factors and HLA Association

Melarsoprol administration for the treatment of late-stage human African trypanosomiasis (HAT) is associated with the development of an unpredictable and badly characterized encephalopathic syndrome (ES), probably of immune origin, that kills approximately 50% of those affected. We investigated the...

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Bibliographic Details
Main Authors: Jorge Seixas, Jorge Atouguia, Teófilo Josenando, Gedeão Vatunga, Constantin Miaka Mia Bilenge, Pascal Lutumba, Christian Burri
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Tropical Medicine and Infectious Disease
Subjects:
human african trypanosomiasis
treatment
melarsoprol
adverse event
encephalopathy
human leukocyte antigen
association study
Online Access:https://www.mdpi.com/2414-6366/5/1/5

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https://www.mdpi.com/2414-6366/5/1/5

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