Anti-Atherosclerotic Activity of (3<i>R</i>)-5-Hydroxymellein from an Endophytic Fungus <i>Neofusicoccum parvum</i> JS-0968 Derived from <i>Vitex rotundifolia</i> through the Inhibition of Lipoproteins Oxidation and Foam Cell Formation

Anti-Atherosclerotic Activity of (3<i>R</i>)-5-Hydroxymellein from an Endophytic Fungus <i>Neofusicoccum parvum</i> JS-0968 Derived from <i>Vitex rotundifolia</i> through the Inhibition of Lipoproteins Oxidation and Foam Cell Formation

An endophytic fungus, <i>Neofusicoccum parvum</i> JS-0968, was isolated from a plant, <i>Vitex rotundifolia</i>. The chemical investigation of its cultures led to the isolation of a secondary metabolite, (3<i>R</i>)-5-hydroxymellein. It has been reported to have a...

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Bibliographic Details
Main Authors: Jae-Yong Kim, Soonok Kim, Sang Hee Shim
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Biomolecules
Subjects:
(3<i>R</i>)-5-hydroxymellein
low-density lipoprotein
high-density lipoprotein
oxidation
foam cell
atherosclerosis
Online Access:https://www.mdpi.com/2218-273X/10/5/715

Internet

https://www.mdpi.com/2218-273X/10/5/715

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