Using TLC-MALDI-TOF to Interrogate In Vitro Peptidyl Proximal Preferences of PARP14 and Glycohydrolase Specificity

Using TLC-MALDI-TOF to Interrogate In Vitro Peptidyl Proximal Preferences of PARP14 and Glycohydrolase Specificity

The transfer of ADP–ribose (ADPr) from nicotinamide adenine dinucleotide (NAD<sup>+</sup>) to target proteins is mediated by a class of human diphtheria toxin-like ADP-ribosyltransferases (ARTDs; previously referred to as poly-ADP–ribose polymerases or PARPs) and the removal of ADPr is c...

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Bibliographic Details
Main Authors: Zeeshan Javed, Hannah H. Nguyen, Kiana K. Harker, Christian M. Mohr, Pia Vano, Sean R. Wallace, Clarissa Silvers, Colin Sim, Soumya Turumella, Ally Flinn, Anthony Moritz, Ian Carter-O’Connell
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Molecules
Subjects:
PARP
PARP14
ADP-Ribose
ARTD
ARTD8
NAD<sup>+</sup>
Online Access:https://www.mdpi.com/1420-3049/28/16/6061

Internet

https://www.mdpi.com/1420-3049/28/16/6061

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