Decreased Plasma Levels of Kynurenine and Kynurenic Acid in Previously Treated and First-Episode Antipsychotic-Naive Schizophrenia Patients

Decreased Plasma Levels of Kynurenine and Kynurenic Acid in Previously Treated and First-Episode Antipsychotic-Naive Schizophrenia Patients

Tryptophan (TRP) catabolites exert neuroactive effects, with the plethora of evidence suggesting that kynurenic acid (KYNA), a catabolite of the kynurenine pathway (KP), acts as the regulator of glutamate and acetylcholine in the brain, contributing to the schizophrenia pathophysiology. Newer eviden...

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Bibliographic Details
Main Authors: Miloš Marković, Nataša Petronijević, Milena Stašević, Ivana Stašević Karličić, Milica Velimirović, Tihomir Stojković, Slavica Ristić, Mina Stojković, Nataša Milić, Tatjana Nikolić
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Cells
Subjects:
schizophrenia
first-episode
blood
plasma
tryptophan
kynurenine
Online Access:https://www.mdpi.com/2073-4409/12/24/2814

Internet

https://www.mdpi.com/2073-4409/12/24/2814

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