Testing if Micro-CT Is Capable of Quantitating the Extent of Proteoglycan-Aggrecan Induced Axial Spondyloarthritis in Mice

Testing if Micro-CT Is Capable of Quantitating the Extent of Proteoglycan-Aggrecan Induced Axial Spondyloarthritis in Mice

ObjectiveInjections of proteoglycan aggrecan (PGA) have been reported to induce axial spondyloarthritis (ax-SpA) in BALB/c mice. It is considered to be a model for radiographic ax-SpA. However, evaluation of the extent of axial disease by histopathological assessment of every intervertebral space is...

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Bibliographic Details
Main Authors: Qing Han, ZhaoHui Zheng, Qiang Liang, Kui Zhang, FengFan Yang, XiangHui Fu, Xing Luo, Jin Ding, Ronghua Xie, WenXiao Zhu, Ping Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Immunology
Subjects:
spondyloarthritis
proteoglycan
aggrecan
BALB/c
animal models
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.681217/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.681217/full

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