Parental Preconception and Pre-Hatch Exposure to a Developmental Insult Alters Offspring’s Gene Expression and Epigenetic Regulations: An Avian Model

Parental Preconception and Pre-Hatch Exposure to a Developmental Insult Alters Offspring’s Gene Expression and Epigenetic Regulations: An Avian Model

Parental exposure to insults was initially considered safe if stopped before conception. In the present investigation, paternal or maternal preconception exposure to the neuroteratogen chlorpyrifos was investigated in a well-controlled avian model (<i>Fayoumi</i>) and compared to pre-hat...

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Bibliographic Details
Main Authors: Issam Rimawi, Gadi Turgeman, Nataly Avital-Cohen, Israel Rozenboim, Joseph Yanai
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
chlorpyrifos
avian model
epigenetic regulation
gene expression
neurogenesis and neurotransmission
parental preconception exposure
Online Access:https://www.mdpi.com/1422-0067/24/5/5047

Internet

https://www.mdpi.com/1422-0067/24/5/5047

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