Topological diversity of chromatin fibers: Interplay between nucleosome repeat length, DNA linking number and the level of transcription

Topological diversity of chromatin fibers: Interplay between nucleosome repeat length, DNA linking number and the level of transcription

The spatial organization of nucleosomes in 30-nm fibers remains unknown in detail. To tackle this problem, we analyzed all stereochemically possible configurations of two-start chromatin fibers with DNA linkers L = 10-70 bp (nucleosome repeat length NRL = 157-217 bp). In our model, the energy of a f...

Full description

Bibliographic Details
Main Authors: Davood Norouzi, Ataur Katebi, Feng Cui, Victor B. Zhurkin
Format: Article
Language:English
Published: AIMS Press 2015-11-01
Series:AIMS Biophysics
Subjects:
chromatin fiber
nucleosome repeat length
DNA linking number
DNA topology
regulation of transcription
Online Access:http://www.aimspress.com/biophysics/article/494/fulltext.html

Internet

http://www.aimspress.com/biophysics/article/494/fulltext.html

Similar Items