Conformational dynamics in the disordered region of human CPEB3 linked to memory consolidation

Conformational dynamics in the disordered region of human CPEB3 linked to memory consolidation

Abstract Background Current understanding of the molecular basis of memory consolidation points to an important function of amyloid formation by neuronal-specific isoforms of the cytoplasmic polyadenylation element binding (CPEB) protein family. In particular, CPEB is thought to promote memory persi...

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Bibliographic Details
Main Authors: D. Ramírez de Mingo, D. Pantoja-Uceda, R. Hervás, M. Carrión-Vázquez, D. V. Laurents
Format: Article
Language:English
Published: BMC 2022-06-01
Series:BMC Biology
Subjects:
Memory consolidation
Intrinsically disordered proteins
NMR spectroscopy
Online Access:https://doi.org/10.1186/s12915-022-01310-6

Internet

https://doi.org/10.1186/s12915-022-01310-6

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