Docking Studies and Biological Evaluation of a Potential β-Secretase Inhibitor of 3-Hydroxyhericenone F from Hericium erinaceus

Docking Studies and Biological Evaluation of a Potential β-Secretase Inhibitor of 3-Hydroxyhericenone F from Hericium erinaceus

Alzheimer’s disease (AD) is the most common neurodegenerative disorder, affecting approximately more than 5% of the population worldwide over the age 65, annually. The incidence of AD is expected to be higher in the next 10 years. AD patients experience poor prognosis and as a consequence new drugs...

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Bibliographic Details
Main Authors: Chen Diling, Yong Tianqiao, Yang Jian, Zheng Chaoqun, Shuai Ou, Xie Yizhen
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Pharmacology
Subjects:
molecular docking
regulatory mechanism
Hericium erinaceus
active pharmaceutical ingredient
functional foods
3-Hydroxyhericenone F
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00219/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00219/full

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