No Association between Single-Nucleotide Polymorphisms of The S1PR1 Gene or Interleukin-17 Levels with Fingolimod Response in A Small Group of Iranian Relapsing-Remitting Multiple Sclerosis Patients: A Case-Control Study
Objective: Multiple sclerosis (MS) has a multi-factorial etiology involving genetic factors. Fingolimod (Gilenya ®,FTY720) modulates the G-protein-coupled sphingosine 1-phosphate (S1P) receptors, S1PR1, 2, 3, 4 and 5. Variationin the human S1PR1 coding sequence results in heterogeneity in the functi...
| Main Authors: | , , |
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| 格式: | 文件 |
| 语言: | English |
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Royan Institute (ACECR), Tehran
2024-03-01
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| 丛编: | Cell Journal |
| 主题: | |
| 在线阅读: | https://www.celljournal.org/article_711247_4c6fdd2bdb75181aa3ed10ff0ce774ad.pdf |