Skin CD4+ memory T cells exhibit combined cluster-mediated retention and equilibration with the circulation

Skin CD4+ memory T cells exhibit combined cluster-mediated retention and equilibration with the circulation

Memory T cells are vital responders to skin inflammation, but cell localization and dynamics of exchange with the bloodstream are not clear. Here the authors use parabiosis and intravital microscopy to show that CD4+memory T cells equilibrate with the circulation and cluster around hair follicles in...

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Bibliographic Details
Main Authors: Nicholas Collins, Xiaodong Jiang, Ali Zaid, Bethany L. Macleod, Jane Li, Chang Ook Park, Ashraful Haque, Sammy Bedoui, William R. Heath, Scott N. Mueller, Thomas S. Kupper, Thomas Gebhardt, Francis R. Carbone
Format: Article
Language:English
Published: Nature Portfolio 2016-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms11514

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https://doi.org/10.1038/ncomms11514

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