Microwave Assisted Organic Synthesis (MAOS) of Small Molecules as Potential HIV-1 Integrase Inhibitors

Microwave Assisted Organic Synthesis (MAOS) of Small Molecules as Potential HIV-1 Integrase Inhibitors

Integrase (IN) represents a clinically validated target for the development of antivirals against human immunodeficiency virus (HIV). In recent years our research group has been engaged in the stucture-function study of this enzyme and in the development of some three-dimensional pharmacophore model...

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Bibliographic Details
Main Authors: Alba Chimirri, Caterina Elisa Faliti, Zeger Debyzer, Rosaria Gitto, Laura De Luca, Sara De Grazia, Stefania Ferro
Format: Article
Language:English
Published: MDPI AG 2011-08-01
Series:Molecules
Subjects:
AIDS
integrase inhibitors
small molecules
MAOS
Online Access:http://www.mdpi.com/1420-3049/16/8/6858/

Internet

http://www.mdpi.com/1420-3049/16/8/6858/

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