Allogenic microglia replacement: A novel therapeutic strategy for neurological disorders

Microglia are resident immune cells in the central nervous system (CNS) that play vital roles in CNS development, homeostasis and disease pathogenesis. Genetic defects in microglia lead to microglial dysfunction, which in turn leads to neurological disorders. The correction of the specific genetic d...

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Bibliographic Details
Main Authors: Yanxia Rao, Bo Peng
Format: Article
Language:English
Published: KeAi Communications Co. Ltd. 2024-03-01
Series:Fundamental Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667325823000778