Pigment Epithelium‐Derived Factor (PEDF) Improves Ischemic Cardiac Functional Reserve Through Decreasing Hypoxic Cardiomyocyte Contractility Through PEDF Receptor (PEDF‐R)

Pigment Epithelium‐Derived Factor (PEDF) Improves Ischemic Cardiac Functional Reserve Through Decreasing Hypoxic Cardiomyocyte Contractility Through PEDF Receptor (PEDF‐R)

BackgroundPigment epithelium‐derived factor (PEDF), which belongs to the noninhibitory serpin family, has shown the ability to stimulate several physiological processes, such as antiangiogenesis, anti‐inflammation, and antioxidation. In the present study, the effects of PEDF on contractility and cal...

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Bibliographic Details
Main Authors: Peng Lu, Yi‐Qian Zhang, Hao Zhang, Yu‐Feng Li, Xiao‐Yu Wang, Hao Xu, Zhi‐Wei Liu, Lei Li, Hong‐Yan Dong, Zhong‐Ming Zhang
Format: Article
Language:English
Published: Wiley 2016-07-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
cardiomyocyte
contractility
myocardial infarction
pigment epithelial‐derived factor
pigment epithelial‐derived factor receptor
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.115.003179

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.115.003179

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