Pyramidal cell axon initial segment in Alzheimer´s disease

Abstract The axon initial segment (AIS) is a region of the neuron that is critical for action potential generation as well as for the regulation of neural activity. This specialized structure—characterized by the expression of different types of ion channels as well as adhesion, scaffolding and cyto...

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Bibliographic Details
Main Authors: Alejandro Antón-Fernández, Gonzalo León-Espinosa, Javier DeFelipe, Alberto Muñoz
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-12700-9