Vaccine-Induced Subcutaneous Granulomas in Goats Reflect Differences in Host–Mycobacterium Interactions between BCG- and Recombinant BCG-Derivative Vaccines

Vaccine-Induced Subcutaneous Granulomas in Goats Reflect Differences in Host–Mycobacterium Interactions between BCG- and Recombinant BCG-Derivative Vaccines

Tuberculous granulomas are highly dynamic structures reflecting the complex host–mycobacterium interactions. The objective of this study was to compare granuloma development at the site of vaccination with BCG and its recombinant derivatives in goats. To characterize the host response, epithelioid c...

Full description

Bibliographic Details
Main Authors: Elisabeth M. Liebler-Tenorio, Johannes Heyl, Nadine Wedlich, Julia Figl, Heike Köhler, Gopinath Krishnamoorthy, Natalie E. Nieuwenhuizen, Leander Grode, Stefan H. E. Kaufmann, Christian Menge
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
tuberculosis
vaccination
recombinant BCG
goat
histology
immunohistochemistry
Online Access:https://www.mdpi.com/1422-0067/23/19/10992

Internet

https://www.mdpi.com/1422-0067/23/19/10992

Similar Items