Genetic and phenotypic analysis of the causal relationship between aging and COVID-19

Ying et al. conduct a multi-instrument Mendelian randomization study looking at the link between aging and COVID-19 risk. They observe an association between genetic variation implicated in longevity and decreased risk of COVID-19 infection and hospitalization, with Notch signaling and immune system...

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Bibliographic Details
Main Authors: Kejun Ying, Ranran Zhai, Timothy V. Pyrkov, Anastasia V. Shindyapina, Marco Mariotti, Peter O. Fedichev, Xia Shen, Vadim N. Gladyshev
Format: Article
Language:English
Published: Nature Portfolio 2021-10-01
Series:Communications Medicine
Online Access:https://doi.org/10.1038/s43856-021-00033-z