Distinct microbiome profiles and biofilms in Leishmania donovani-driven cutaneous leishmaniasis wounds

Abstract The endemic strain of Leishmania donovani in Sri Lanka causes cutaneous leishmaniasis (CL) rather than more common visceral form. We have visualized biofilms and profiled the microbiome of lesions and unaffected skin in thirty-nine CL patients. Twenty-four lesions (61.5%) were biofilm-posit...

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Bibliographic Details
Main Authors: T. D. Jayasena Kaluarachchi, Paul M. Campbell, Rajitha Wickremasinghe, Shalindra Ranasinghe, Renu Wickremasinghe, Surangi Yasawardene, Hiromel De Silva, Chandrani Menike, M. C. K. Jayarathne, Subodha Jayathilake, Ayomi Dilhari, Andrew J. McBain, Manjula M. Weerasekera
Format: Article
Language:English
Published: Nature Portfolio 2021-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-02388-8