Cargo properties play a critical role in myosin Va-driven cargo transport along actin filaments

Cargo properties play a critical role in myosin Va-driven cargo transport along actin filaments

High-resolution experiments revealed that a single myosin-Va motor can transport micron-sized cargo on actin filaments in a stepwise manner. However, intracellular cargo transport is mediated through the dense actin meshwork by a team of myosin Va motors. The mechanism of how motors interact mechani...

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Bibliographic Details
Main Authors: Arthur J. Michalek, M. Yusuf Ali
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:Biochemistry and Biophysics Reports
Subjects:
Myosin Va
Cargo transport
Tether force
Rigidity
Stochastic model
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580821002880

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http://www.sciencedirect.com/science/article/pii/S2405580821002880

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