Interaction between NANOS2 and the CCR4-NOT deadenylation complex is essential for male germ cell development in mouse.

Nanos is one of the evolutionarily conserved proteins implicated in germ cell development and we have previously shown that it interacts with the CCR4-NOT deadenylation complex leading to the suppression of specific RNAs. However, the molecular mechanism and physiological significance of this intera...

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Bibliographic Details
Main Authors: Atsushi Suzuki, Rie Saba, Kei Miyoshi, Yoshinori Morita, Yumiko Saga
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3308992?pdf=render