Increased White Matter Inflammation in Aging- and Alzheimer’s Disease Brain

Increased White Matter Inflammation in Aging- and Alzheimer’s Disease Brain

Chronic neuroinflammation, which is primarily mediated by microglia, plays an essential role in aging and neurodegeneration. It is still unclear whether this microglia-induced neuroinflammation occurs globally or is confined to distinct brain regions. In this study, we investigated microglia activit...

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Bibliographic Details
Main Authors: Divya Raj, Zhuoran Yin, Marjolein Breur, Janine Doorduin, Inge R. Holtman, Marta Olah, Ietje J. Mantingh-Otter, Debby Van Dam, Peter P. De Deyn, Wilfred den Dunnen, Bart J. L. Eggen, Sandra Amor, Erik Boddeke
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Molecular Neuroscience
Subjects:
white matter
microglia
neuroinflammation
aging
Alzheimer’s disease
Online Access:http://journal.frontiersin.org/article/10.3389/fnmol.2017.00206/full

Internet

http://journal.frontiersin.org/article/10.3389/fnmol.2017.00206/full

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