Molecular and cellular dynamics of the Toll-like receptor 4 pathway.

As well as being the primary signaling receptor for bacterial endotoxin or lipopolysaccharide Toll-like receptor 4 function is modulated by numerous factors not only in the context of microbial pathogenesis but also autoimmune and allergic diseases. TLR4 is subject to multiple levels of endogenous c...

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Bibliographic Details
Main Authors: Nick eGay, Ardiyanto eLiaunardy-Jopeace
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00473/full