HDAC6 Inhibition Extinguishes Autophagy in Cancer: Recent Insights

HDAC6 Inhibition Extinguishes Autophagy in Cancer: Recent Insights

Autophagy is an essential intracellular catabolic mechanism involved in the degradation and recycling of damaged organelles regulating cellular homeostasis and energy metabolism. Its activation enhances cellular tolerance to various stresses and is known to be involved in drug resistance. In cancer,...

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Bibliographic Details
Main Authors: Eugenia Passaro, Chiara Papulino, Ugo Chianese, Antonella Toraldo, Raffaella Congi, Nunzio Del Gaudio, Maria Maddalena Nicoletti, Rosaria Benedetti, Lucia Altucci
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cancers
Subjects:
autophagy
epigenetics
HDAC inhibitors
HDAC6
drug resistance
cancer
Online Access:https://www.mdpi.com/2072-6694/13/24/6280

Internet

https://www.mdpi.com/2072-6694/13/24/6280

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