Pharmacodynamic sodium channel blockers-induced seizure aggravation in patients with newly diagnosed focal epilepsy

Pharmacodynamic sodium channel blockers-induced seizure aggravation in patients with newly diagnosed focal epilepsy

Pharmacodynamic aggravation (PA) is an unpredictable increase in the frequency, the severity of existing seizures, and/or development of new seizure types despite rational (adequate for seizure type and epilepsy form) antiepileptic drug (AED) prescription. Many mechanisms and predictors of its devel...

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Bibliographic Details
Main Authors: V. A. Karlov, P. N. Vlasov, A. M. Azhigova, A. B. Kozhokaru, A. S. Orlova
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2021-08-01
Series:Неврология, нейропсихиатрия, психосоматика
Subjects:
focal epilepsy
pharmacodynamics aggravation
paradoxical increase in seizure frequency
paradoxical effect
epileptiform activity index
sodium channel blockers
antiepileptic drugs
Online Access:https://nnp.ima-press.net/nnp/article/view/1629

Internet

https://nnp.ima-press.net/nnp/article/view/1629

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