Antiproliferative and Cytotoxic Cytochalasins from <i>Sparticola triseptata</i> Inhibit Actin Polymerization and Aggregation

Antiproliferative and Cytotoxic Cytochalasins from <i>Sparticola triseptata</i> Inhibit Actin Polymerization and Aggregation

Laying the groundwork on preliminary structure–activity relationship study relating to the disruptive activity of cytochalasan derivatives on mammalian cell actin cytoskeleton, we furthered our study on the cytochalasans of the Dothideomycetes fungus, <i>Sparticola triseptata</i>. A new...

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Bibliographic Details
Main Authors: Katherine Yasmin M. Garcia, Mark Tristan J. Quimque, Christopher Lambert, Katharina Schmidt, Gian Primahana, Theresia E. B. Stradal, Andreas Ratzenböck, Hans-Martin Dahse, Chayanard Phukhamsakda, Marc Stadler, Frank Surup, Allan Patrick G. Macabeo
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Journal of Fungi
Subjects:
<i>Sparticola triseptata</i>
structure elucidation
ECD–TDDFT
antiproliferative
cytotoxic
actin inhibitors
Online Access:https://www.mdpi.com/2309-608X/8/6/560

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https://www.mdpi.com/2309-608X/8/6/560

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