Preparation of Sorafenib tosylate self-emulsified drug delivery system and the effect on combination therapy with Bosutinib against HCT116/SW1417 cells
The Sorafenib tosylate (ST) emulsified drug delivery system (ST-SEDDS) was designed and characterized in response to the poor solubility and bioavailability of ST. ST-SEDDS formed fine emulsions with a mean diameter of 158.3 ± 1.4 nm, a narrow size distribution (PDI 0.257), and a Zeta potential of –...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-01-01
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| Series: | Results in Chemistry |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211715622001047 |