Dihydropyrimidine Dehydrogenase (DPD) as a Bridge between the Immune Microenvironment of Colon Cancers and 5-FU Resistance

Dihydropyrimidine Dehydrogenase (DPD) as a Bridge between the Immune Microenvironment of Colon Cancers and 5-FU Resistance

Background: The purpose of the present study was to investigate the role of the 5-Fluorouracil (5-FU) resistance-related factor dihydropyrimidine dehydrogenase (DPD) in tumor immunity and prognosis and to study the relationship between drug resistance and the immune microenvironment of colon cancer....

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Bibliographic Details
Main Authors: Zhongze Cui, Shuang He, Feifei Wen, Lizhen Lu, Lei Xu, Han Wu, Shuhua Wu
Format: Article
Language:English
Published: IMR Press 2023-04-01
Series:Frontiers in Bioscience-Landmark
Subjects:
colon cancer
dpd
5-fu resistance
microsatellite instability
tumor mutational burden
tumor immune microenvironment
Online Access:https://www.imrpress.com/journal/FBL/28/4/10.31083/j.fbl2804080

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https://www.imrpress.com/journal/FBL/28/4/10.31083/j.fbl2804080

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