Overexpression of MicroRNA-10a in Germ Cells Causes Male Infertility by Targeting Rad51 in Mouse and Human

Overexpression of MicroRNA-10a in Germ Cells Causes Male Infertility by Targeting Rad51 in Mouse and Human

Spermatogenesis is a complicated process including spermatogonial stem cells self-renewal and differentiates into mature spermatozoa. MicroRNAs (miRNAs) as a class of small non-coding RNAs play a crucial role during the process of spermatogenesis. However, the function of a plenty of miRNAs on sperm...

Full description

Bibliographic Details
Main Authors: Huihui Gao, Hui Wen, Congcong Cao, Daqian Dong, Chenhao Yang, Shengsong Xie, Jin Zhang, Xunbin Huang, Xingxu Huang, Shuiqiao Yuan, Wuzi Dong
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Physiology
Subjects:
miRNA-10a
spermatogenesis
overexpression mice
Rad51
meiosis
non-obstructive azoospermia
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00765/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2019.00765/full

Similar Items