Ex vivo gut cultures of Aedes aegypti are efficiently infected by mosquito-borne alpha- and flaviviruses

Ex vivo gut cultures of Aedes aegypti are efficiently infected by mosquito-borne alpha- and flaviviruses

ABSTRACT Aedes aegypti mosquitoes can transmit several arboviruses, including chikungunya virus (CHIKV), dengue virus (DENV), and Zika virus (ZIKV). When blood-feeding on a virus-infected human, the mosquito ingests the virus into the midgut (stomach), where it replicates and must overcome the midgu...

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Bibliographic Details
Main Authors: Ana Lucia Rosales Rosas, Lanjiao Wang, Sara Goossens, Arno Cuvry, Li-Hsin Li, Nanci Santos-Ferreira, Alina Soto, Kai Dallmeier, Joana Rocha-Pereira, Leen Delang
Format: Article
Language:English
Published: American Society for Microbiology 2023-10-01
Series:Microbiology Spectrum
Subjects:
arbovirus
mosquito gut
ex vivo
antivirals
Online Access:https://journals.asm.org/doi/10.1128/spectrum.05195-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.05195-22

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