Stability selection enhances feature selection and enables accurate prediction of gestational age using only five DNA methylation sites

Stability selection enhances feature selection and enables accurate prediction of gestational age using only five DNA methylation sites

Abstract Background DNA methylation (DNAm) is robustly associated with chronological age in children and adults, and gestational age (GA) in newborns. This property has enabled the development of several epigenetic clocks that can accurately predict chronological age and GA. However, the lack of ove...

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Bibliographic Details
Main Authors: Kristine L. Haftorn, Julia Romanowska, Yunsung Lee, Christian M. Page, Per M. Magnus, Siri E. Håberg, Jon Bohlin, Astanand Jugessur, William R. P. Denault
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Clinical Epigenetics
Subjects:
DNA methylation
Epigenetics
Gestational age
Illumina MethylationEPIC BeadChip
Epigenetic clock
Stability selection
Online Access:https://doi.org/10.1186/s13148-023-01528-3

Internet

https://doi.org/10.1186/s13148-023-01528-3

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