Metabolic effects of CCL5 deficiency in lean and obese mice

Metabolic effects of CCL5 deficiency in lean and obese mice

Accumulation and activation of immunocytes in adipose tissues are essential to obesity-induced inflammation and insulin resistance. Chemokines are pivotal for the recruitment of immunocytes in adipose tissue during obesity. Chemokine (C-C motif) ligand 5 (CCL5) plays a vital role in the recruitment...

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Bibliographic Details
Main Authors: Hui Zhou, Xiyan Liao, Qin Zeng, Haowei Zhang, Jianfeng Song, Wanyu Hu, Xiaoxiao Sun, Yujin Ding, Dandan Wang, Yalun Xiao, Tuo Deng
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
obesity
adipose inflammation
CCL5
chemokine
insulin resistance
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1059687/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1059687/full

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