Hypoxia Regulates the Self-Renewal of Endometrial Mesenchymal Stromal/Stem-like Cells via Notch Signaling

Hypoxia Regulates the Self-Renewal of Endometrial Mesenchymal Stromal/Stem-like Cells via Notch Signaling

Human endometrium is an incredibly dynamic tissue undergoing cyclic regeneration and shedding during a woman’s reproductive life. Endometrial mesenchymal stromal/stem-like cells (eMSC) contribute to this process. A hypoxic niche with low oxygen levels has been reported in multiple somatic stem cell...

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Bibliographic Details
Main Authors: Sisi Zhang, Rachel W.S. Chan, Ernest H.Y. Ng, William S.B. Yeung
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:International Journal of Molecular Sciences
Subjects:
endometrial mesenchymal stromal/stem cells
label-retaining stromal cells
hypoxia
Notch signaling
HIF-1α
Online Access:https://www.mdpi.com/1422-0067/23/9/4613

Internet

https://www.mdpi.com/1422-0067/23/9/4613

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