Characterization of fish‐specific IFNγ‐related binding with a unique receptor complex and signaling through a novel pathway

Characterization of fish‐specific IFNγ‐related binding with a unique receptor complex and signaling through a novel pathway

Unlike mammals, fish express two type II interferons, IFNγ and fish‐specific IFNγ (IFNγ‐related or IFNγrel). We previously reported the presence of two IFNγrel genes, IFNγrel 1 and IFNγrel 2, which exhibit potent antiviral activity in the Ginbuna crucian carp, Carassius auratus langsdorfii. We also...

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Bibliographic Details
Main Authors: Yasuhiro Shibasaki, Takeshi Yabu, Hajime Shiba, Tadaaki Moritomo, Nobuhiro Mano, Teruyuki Nakanishi
Format: Article
Language:English
Published: Wiley 2024-04-01
Series:FEBS Open Bio
Subjects:
cytokine receptor
IFNγ‐related
signal transduction
STAT
type II interferon
Online Access:https://doi.org/10.1002/2211-5463.13769

Internet

https://doi.org/10.1002/2211-5463.13769

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