Characterization of fish‐specific IFNγ‐related binding with a unique receptor complex and signaling through a novel pathway
Unlike mammals, fish express two type II interferons, IFNγ and fish‐specific IFNγ (IFNγ‐related or IFNγrel). We previously reported the presence of two IFNγrel genes, IFNγrel 1 and IFNγrel 2, which exhibit potent antiviral activity in the Ginbuna crucian carp, Carassius auratus langsdorfii. We also...
Main Authors: | Yasuhiro Shibasaki, Takeshi Yabu, Hajime Shiba, Tadaaki Moritomo, Nobuhiro Mano, Teruyuki Nakanishi |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2024-04-01
|
Series: | FEBS Open Bio |
Subjects: | |
Online Access: | https://doi.org/10.1002/2211-5463.13769 |
Similar Items
-
Bridging Radiotherapy to Immunotherapy: The IFN–JAK–STAT Axis
by: Lewis Zhichang Shi, et al.
Published: (2021-11-01) -
Role of interferon-gamma (IFN-γ) and IFN-γ receptor 1/2 (IFNγR1/2) in regulation of immunity, infection, and cancer development: IFN-γ-dependent or independent pathway
by: Huihui Ding, et al.
Published: (2022-11-01) -
Human Cytomegalovirus UL23 Antagonizes the Antiviral Effect of Interferon-γ by Restraining the Expression of Specific IFN-Stimulated Genes
by: Hankun Wang, et al.
Published: (2023-04-01) -
Inflammatory activation of the FcγR and IFNγR pathways co-influences the differentiation and activity of osteoclasts
by: Bettina Groetsch, et al.
Published: (2022-09-01) -
Identification and characterization of interferon-γ signaling-based personalized heterogeneity and therapeutic strategies in patients with pancreatic cancer
by: Xu Chen, et al.
Published: (2023-10-01)