Thiol Redox Transitions in Cell Signaling: a Lesson from N-Acetylcysteine

The functional status of cells is under the control of external stimuli affecting the function of critical proteins and eventually gene expression. Signal sensing and transduction by messengers to specific effectors operate by post-translational modification of proteins, among which thiol redox swit...

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Bibliographic Details
Main Authors: Tiziana Parasassi, Roberto Brunelli, Graziella Costa, Marco De Spirito, Ewa Krasnowska, Thomas Lundeberg, Eugenia Pittaluga, Fulvio Ursini
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2010.104