Single VHH-directed BCMA CAR-NK cells for multiple myeloma

Single VHH-directed BCMA CAR-NK cells for multiple myeloma

Abstract Natural killer (NK) cells are promising alternatives for the production of “off-the-shelf” CAR products, posing a lower risk of cytokine release syndrome (CRS) than CAR-T cells. We synthesized four single VHH-directed anti-BCMA CARs, incorporating various intracellular regions (2B4 versus C...

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Bibliographic Details
Main Authors: Quan Ren, Yingling Zu, Hongchang Su, Qiumei Lu, Bin Xiang, Yanping Luo, Jishuai Zhang, Yongping Song
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Experimental Hematology & Oncology
Subjects:
BCMA
CAR-NK
Multiple Myeloma
VHH
Online Access:https://doi.org/10.1186/s40164-023-00461-8

Internet

https://doi.org/10.1186/s40164-023-00461-8

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