The multicopper ferroxidase hephaestin enhances intestinal iron absorption in mice.

Hephaestin is a vertebrate multicopper ferroxidase important for the transfer of dietary iron from intestinal cells to the blood. Hephaestin is mutated in the sex-linked anemia mouse, resulting in iron deficiency. However, sex-linked anemia mice still retain some hephaestin ferroxidase activity. The...

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Bibliographic Details
Main Authors: Brie K Fuqua, Yan Lu, Deepak Darshan, David M Frazer, Sarah J Wilkins, Natalie Wolkow, Austin G Bell, JoAnn Hsu, Catherine C Yu, Huijun Chen, Joshua L Dunaief, Gregory J Anderson, Chris D Vulpe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4045767?pdf=render