Metastasis-associated protein 1 (MTA1) is transferred by exosomes and contributes to the regulation of hypoxia and estrogen signaling in breast cancer cells

Abstract Background Exosomes are small membrane-bound vesicles that contribute to tumor progression and metastasis by mediating cell-to-cell communication and modifying the tumor microenvironment at both local and distant sites. However, little is known about the predominant factors in exosomes that...

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Bibliographic Details
Main Authors: Bethany N. Hannafon, Amy L. Gin, Yi-Fan Xu, Matthew Bruns, Cameron L. Calloway, Wei-Qun Ding
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Cell Communication and Signaling
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12964-019-0325-7