CRSCNV: A Cross-Model-Based Statistical Approach to Detect Copy Number Variations in Sequence Data

Copy number variation (CNV) is an important type of mutation in the human genome, and is significantly associated with cancer and other diseases. Accurate detection of CNVs in tumor genomes is crucial for biologists aiming to understand tumorigenesis. One of the key steps in this task is to establis...

Full description

Bibliographic Details
Main Authors: Guojun Liu, Xiguo Yuan, Junying Zhang, Haiyong Zhao, Junping Li, Junbo Duan
Format: Article
Language:English
Published: IEEE 2020-01-01
Series:IEEE Access
Subjects:
Online Access:https://ieeexplore.ieee.org/document/8943185/