Leptin and melatonin’s effects on OVX rodents’ bone metabolism

PurposeThis study aims to examine the effects of leptin and melatonin intervention on bone metabolism in ovariectomize (OVX) rodents, as well as their potential mechanisms of action.MethodsPrepare an OVX model of osteoporosis in rodents and validate the model by collecting bilateral tibia samples fo...

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Bibliographic Details
Main Authors: Zhenen Lin, Guanshu Yu, Shengren Xiong, Yu Lin, Zhaohui Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1185476/full