A20 (TNFAIP3) alleviates viral myocarditis through ADAR1/miR-1a-3p-dependent regulation

A20 (TNFAIP3) alleviates viral myocarditis through ADAR1/miR-1a-3p-dependent regulation

Abstract Objective To investigate the effect of A20 and how A20 is regulated in viral myocarditis (VMC). Methods BABL/C mice, primary neonatal rat cardiomyocytes and H9c2 cells were infected with Coxsackie virus B3 (CVB3) to establish animal and cellular models of VMC. H&E staining revealed the...

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Bibliographic Details
Main Authors: Bin Li, Xing Xie
Format: Article
Language:English
Published: BMC 2022-01-01
Series:BMC Cardiovascular Disorders
Subjects:
A20
miR-1a-3p
ADAR1
Dicer
Viral myocarditis
Inflammation
Online Access:https://doi.org/10.1186/s12872-021-02438-z

Internet

https://doi.org/10.1186/s12872-021-02438-z

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