Adenine Combined with Cisplatin Promotes Anticancer Activity against Hepatocellular Cancer Cells through AMPK-Mediated p53/p21 and p38 MAPK Cascades

Adenine Combined with Cisplatin Promotes Anticancer Activity against Hepatocellular Cancer Cells through AMPK-Mediated p53/p21 and p38 MAPK Cascades

Cisplatin has been widely used in cancer treatments. Recent evidence indicates that adenine has potential anticancer activities against various types of cancers. However, the effects of the combination of adenine and cisplatin on hepatocellular carcinoma (HCC) cells remain sketchy. Here, our objecti...

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Bibliographic Details
Main Authors: Jhen-Yu Huang, You-Cian Lin, Han-Min Chen, Jiun-Tsai Lin, Shao-Hsuan Kao
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Pharmaceuticals
Subjects:
adenine
cisplatin
hepatocellular carcinoma cells
AMP-activated protein kinase
apoptosis
Online Access:https://www.mdpi.com/1424-8247/15/7/795

Internet

https://www.mdpi.com/1424-8247/15/7/795

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