Decreased expression of H19/miR-675 ameliorates muscle atrophy by regulating the IGF1R/Akt/FoxO signaling pathway

Decreased expression of H19/miR-675 ameliorates muscle atrophy by regulating the IGF1R/Akt/FoxO signaling pathway

Abstract Background Long non-coding RNA (lncRNA) H19 is one of the most highly expressed and conserved transcripts in mammalian development, and its functions have been fully discussed in many contexts including tumorigenesis and skeletal muscle development. However, its exact role in muscle atrophy...

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Bibliographic Details
Main Authors: He Zhang, Fei Wang, Xiangsheng Pang, Yue Zhou, Shiming Li, Wenjiong Li, Peng Zhang, Xiaoping Chen
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Molecular Medicine
Subjects:
LncRNA H19
miR-675
Muscle atrophy
Hindlimb suspension
Starvation
IGF1R
Online Access:https://doi.org/10.1186/s10020-023-00683-w

Internet

https://doi.org/10.1186/s10020-023-00683-w

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