Shortening of Zika virus CD-loop reduces neurovirulence while preserving antigenicity.

Zika virus (ZIKV) is a mosquito-borne positive sense RNA virus. Recently, ZIKV emerged into the Western hemisphere as a human health threat, with severe disease associated with developmental and neurological complications. The structural envelope protein of ZIKV and other neurotropic flaviviruses co...

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Bibliographic Details
Main Authors: Kenneth H Dinnon Iii, Emily N Gallichotte, Ethan J Fritch, Vineet D Menachery, Ralph S Baric
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-03-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC6424462?pdf=render