CRISPR-based m6A modification and its potential applications in telomerase regulation

CRISPR-based m6A modification and its potential applications in telomerase regulation

Telomerase determines cell lifespan by controlling chromosome stability and cell viability, m6A epigenetic modification plays an important role in the regulation of telomerase activity. Using CRISPR epigenome editing to analyze specific m6A modification sites in telomerase will provide an important...

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Bibliographic Details
Main Authors: Mingliang Yi, Mingyue Wang, Yongjie Xu, Zhikun Cao, Yinghui Ling, Zijun Zhang, Hongguo Cao
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
CRISPR system
m6A modification
epigenetic regulation
telomere
telomerase
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1200734/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2023.1200734/full

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