ATPase Activity of Bacillus subtilis RecA Affects the Dynamic Formation of RecA Filaments at DNA Double Strand Breaks

ATPase Activity of Bacillus subtilis RecA Affects the Dynamic Formation of RecA Filaments at DNA Double Strand Breaks

ABSTRACT RecA plays a central role in DNA repair and is a main actor involved in homologous recombination (HR). In vivo, RecA forms filamentous structures termed “threads,” which are essential for HR, but whose nature is still ill defined. We show that RecA from Bacillus subtilis having lower ATP bi...

Full description

Bibliographic Details
Main Authors: Rogelio Hernández-Tamayo, Niklas Steube, Thomas Heimerl, Georg K. A. Hochberg, Peter L. Graumann
Format: Article
Language:English
Published: American Society for Microbiology 2022-12-01
Series:mSphere
Subjects:
homologous recombination
RecA
DNA break repair
Bacillus subtilis
DNA repair
double strand break repair
Online Access:https://journals.asm.org/doi/10.1128/msphere.00412-22

Internet

https://journals.asm.org/doi/10.1128/msphere.00412-22

Similar Items