Association of Increased Receptor-Binding Avidity of Influenza A(H9N2) Viruses with Escape from Antibody-Based Immunity and Enhanced Zoonotic Potential

Association of Increased Receptor-Binding Avidity of Influenza A(H9N2) Viruses with Escape from Antibody-Based Immunity and Enhanced Zoonotic Potential

We characterized 55 influenza A(H9N2) viruses isolated in Pakistan during 2014–2016 and found that the hemagglutinin gene is of the G1 lineage and that internal genes have differentiated into a variety of novel genotypes. Some isolates had up to 4-fold reduction in hemagglutination inhibition titers...

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Bibliographic Details
Main Authors: Joshua E. Sealy, Tahir Yaqub, Thomas P. Peacock, Pengxiang Chang, Burcu Ermetal, Anabel Clements, Jean-Remy Sadeyen, Arslan Mehboob, Holly Shelton, Juliet E. Bryant, Rod S. Daniels, John W. McCauley, Munir Iqbal
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2019-01-01
Series:Emerging Infectious Diseases
Subjects:
receptor-binding avidity
influenza A(H9N2) virus
viruses
influenza
escape
antibody-based immunity
Online Access:https://wwwnc.cdc.gov/eid/article/25/1/18-0616_article

Internet

https://wwwnc.cdc.gov/eid/article/25/1/18-0616_article

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