Advanced Lung Adenocarcinoma Patient with ERBB2 Amplification Identified by Comprehensive Genomic Profiling Benefits from Trastuzumab

For non-small-cell lung cancer (NSCLC) patients without established actionable alterations in genes such as EGFR or ALK, options for targeted therapy remain limited in clinical practice. About 5% of lung adenocarcinoma patients have tumors with ERBB2 genetic alterations, with even fewer patients har...

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Bibliographic Details
Main Authors: Chi-Wei Tao, Mei-Yin Chen, Ching-Min Tseng, Nina Lapke, Shu-Jen Chen, Kien Thiam Tan
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Case Reports in Oncological Medicine
Online Access:http://dx.doi.org/10.1155/2020/9072173