Simvastatin Improves Microcirculatory Function in Nonalcoholic Fatty Liver Disease and Downregulates Oxidative and ALE-RAGE Stress

Simvastatin Improves Microcirculatory Function in Nonalcoholic Fatty Liver Disease and Downregulates Oxidative and ALE-RAGE Stress

Increased reactive oxidative stress, lipid peroxidation, inflammation, and fibrosis, which contribute to tissue damage and development and progression of nonalcoholic liver disease (NAFLD), play important roles in microcirculatory disorders. We investigated the effect of the modulatory properties of...

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Bibliographic Details
Main Authors: Evelyn Nunes Goulart da Silva Pereira, Beatriz Peres de Araujo, Karine Lino Rodrigues, Raquel Rangel Silvares, Carolina Souza Machado Martins, Edgar Eduardo Ilaquita Flores, Caroline Fernandes-Santos, Anissa Daliry
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Nutrients
Subjects:
nonalcoholic fatty liver disease
simvastatin
microcirculation
liver
adipose tissue
Online Access:https://www.mdpi.com/2072-6643/14/3/716

Internet

https://www.mdpi.com/2072-6643/14/3/716

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