SERPINs—From Trap to Treatment

Excessive enzyme activity often has pathological consequences. This for example is the case in thrombosis and hereditary angioedema, where serine proteases of the coagulation system and kallikrein-kinin system are excessively active. Serine proteases are controlled by SERPINs (serine protease inhibi...

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Bibliographic Details
Main Authors: Wariya Sanrattana, Coen Maas, Steven de Maat
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2019.00025/full